In A League of Their Own, Tom Hanks' character signs a baseball "Avoid the clap, Jimmy Duggan" and gives it to two children.
In an acting assignment Kramer, from Seinfeld, was assigned to act out the symptoms of gonorrhea while doctors guessed the disease.
In the song "So What", originally by the Anti-Nowhere League, the line "I've had crabs, I've had lice, I've had the clap and that ain't nice"
In Big L's song "The Clinic (Shoulda Worn a Rubber)" he decribes how his boldness of not wearing protection led to him contracting gonorrhea from various women.
